This study analyses changes in magnitude, frequency, and seasonality of moderate low and high flows for 93 catchments in Switzerland. In lower-lying catchments (below 1500 m a.s.l.), moderate low-flow magnitude (frequency) will decrease (increase). In Alpine catchments (above 1500 m a.s.l.), moderate low-flow magnitude (frequency) will increase (decrease). Moderate high flows tend to occur more frequent, and their magnitude increases in most catchments except some Alpine catchments.