The Yangtze River basin in China is home to more than 400 million people and susceptible to major floods. We used projections of future precipitation and temperature from 35 of the most recent global climate models and applied this to a hydrological model of the Yangtze. Changes in the annual discharge varied between a 29.8 % decrease and a 16.0 % increase. The main reason for the difference between the models was the predicted expansion of the summer monsoon north and and west into the basin.