Dear authors

After my own assessment of your manuscript I agree with both reviewers, that your manuscript needs some moderate to minor revisions. Please submit a revised version addressing the all comments by the reviewers, including a clear statement of the hypothesis, and improved description of the methods, and the structure of the discussion (as stated by reviewers #1 and #2). A more precise use of terminology is needed (to avoid confusion as expressed by reviewer #1). Though those are the main issues, please address all reviewers’ comments in your revised manuscript (as you already stated in your responses posted in the discussion stage).

Best Regards,
Patricia Saco

The authors have carefully addressed all the reviewers concerns in both the revised manuscript and the response letter. The revised manuscript has been substantially improved and is now ready for publication.